Macrolide antibiotics are effective and safe, therefore they are often prescribed to children with various infectious diseases. These include the drug "Fromilid". To make it easier to give an antibiotic to a small child, one of its dosage forms is a suspension. It is in demand for sinusitis, otitis media, bronchitis and other diseases caused by harmful bacteria.
Release form and composition
Fromilid for suspension preparation is produced by KRKA from Slovenia in the form of granules placed in dark glass bottles with a volume of 100 ml. The bottle comes with a plastic measuring syringe with 1 to 5 ml markings. One bottle contains 25 grams of granules. They are small in size, light yellow or white in color and smell like a banana. Their main ingredient is clarithromycin in an amount of 1.5 grams in one bottle.
When water is added to the inside of the vial, the granules dissolve to form a homogeneous yellowish-white suspension with a banana aroma and sweet taste. She is prescribed for children over six months old. 5 milliliters of this liquid medicine (in one dosing syringe) contains 125 mg of clarithromycin. It is supplemented with sucrose, citric acid, povidone, banana flavor and several other excipients.
In addition to suspension, Fromilid is also available in solid form. It is an oval tablet in a yellow film shell, containing 250 mg or 500 mg of clarithromycin. In childhood, such "Fromilid" is used from the age of 12. There are no other forms (capsules, injections, drops, etc.) for such a medicine.
Operating principle
The drug has an antibacterial effect due to the ability of clarithromycin to influence ribosomes in the cells of pathogens, which leads to suppression of protein synthesis. The drug affects the most common pathogenic microbes, including pneumococcus, Haemophilus influenzae, Staphylococcus aureus and gonococcus. Fromilid is also effective against chlamydia, mycobacteria, legionella and many other pathogens.
All sensitive microorganisms are indicated in the paper instructions that are in the box with the bottle.
Indications
The reason for prescribing "Fromilid" to a child is an infectious disease caused by one or more microorganisms that are sensitive to clarithromycin. For example, a suspension is prescribed when:
- acute bronchitis;
- otitis media;
- tonsillopharyngitis;
- bacterial pneumonia;
- skin infections;
- infection with mycobacteria and other diseases.
Contraindications
"Fromilid" is not prescribed for:
- hypersensitivity to any of the ingredients of the granules;
- allergies to any antibacterial drug from the macrolide group;
- severe kidney disease;
- heart rhythm disturbances;
- hypokalemia;
- severe liver failure.
Side effects
The digestive tract of some children reacts to the suspension with pain, diarrhea, distorted taste, nausea, and other negative symptoms. Less commonly, the drug causes sleep disturbances, dizziness, candidal stomatitis, nervous condition, allergic rash, changes in blood chemistry parameters, and so on.
If such side effects occur, you should stop treatment and consult a specialist.
Instructions for use
To make sweet syrup from granules, you need to pour 42 ml of water into the bottle. To do this, take purified or non-hot boiled water. It is best to pour the liquid into the bottle in several stages - first add only a portion and mix well, and then add water to the mark on the bottle.
You need to collect the medicine from the bottle with a measuring syringe, which is placed in a box along with the bottle. Since the ingredients of the suspension settle to the bottom during storage, the medicine is shaken before each use. When the child has swallowed the drug, it is advisable to offer him a little water so that the remaining medicine in the mouth can enter the stomach. After giving the product to the child, the syringe is washed with water and left to dry until the next use.
The daily dosage of "Fromilid" for a child is calculated by weight and is 15 mg of active compound per 1 kg of the patient's body weight. Having calculated the required amount of suspension per day, it is divided into 2 doses with an interval of 12 hours. In addition, you can see the approximate dosage of the medication in the paper annotation attached to the bottle.
The child can take the suspension both before meals and at any other time, since the diet does not affect the treatment with this drug. The duration of use of "Fromilid" usually ranges from 5 to 10 days.
Overdose
If you accidentally exceed the dose of the drug, it can cause nausea, abdominal pain and other negative symptoms from the gastrointestinal tract. If an overdose is detected, gastric lavage and symptomatic therapy are recommended.
Interaction with other drugs
The use of "Fromilid" should not be combined with treatment with many other means, among which drugs of phenytoin, colchicine, theophylline, cyclosporine, terfenadine are noted.
If the child is already taking any medications, then their compatibility with the suspension should be checked with the doctor or in the annotation.
Terms of sale and storage
To buy Fromilid suspension at a pharmacy, you need to get a prescription from your doctor. The shelf life of the medicine, if the bottle is sealed, is 2 years. It should be kept at home at temperatures up to +30 degrees. After mixing with water, Fromilid can be stored at a temperature not higher than +25 degrees for a maximum of 14 days. The storage area should be dark and hidden from children.
Reviews
In most cases, Fromilid responds well, noting its high efficiency in various bacterial infections. The preparation in suspension is praised for its convenient shape, fast healing effect, good tolerance and pleasant taste. The disadvantages of the remedy include many contraindications and a high price.
Analogs
If it is not possible to use "Fromilid", it is permissible to replace it with another drug based on clarithromycin, for example, "Klacid" suspension. Also, other macrolide antibiotics, such as Hemomycin, Azitrox, Macropen, Sumamed, Vilprafen and other drugs, are often used as analogues of Fromilid. If a small patient is found to be allergic to such antimicrobial agents, the doctor will prescribe an antibiotic of another group, for example, "Ospamox" or "Augmentin".
For information on when a child should be given antibiotics, see below.
