Antidiarrheal drug Stopdiar in pediatric practice
Stopdiar is considered an effective drug against diarrhea, it is used for diarrhea in adults, children (including babies), and pregnant women. This pharmacological agent is widely used in pediatrics, as it has a high level of safety and is produced in various forms suitable for children of different ages.
Brief description of Stopdiar
The main active ingredient
Nifuroxazide - the main active ingredient of the drug. It is not an antibiotic, but it is antibacterial. The agent belongs to the group of nitrofurans.
Differences from antibiotics:
- does not destroy healthy intestinal flora;
- is not absorbed into the blood from the gastrointestinal tract;
- does not have a systemic effect;
- fights only against pathogenic microbes that have entered the intestines.
What is the mechanism of action of Stopdiar
The active ingredient works well against bacteria:
- clostridia;
- shigella;
- salmonella;
- eshirichii koli;
- cholera vibrio;
- campylobacter;
- pathogenic staphylococci;
- halophilic vibrio.
Bacteria Citrobacter, Proteus and Enterobacter have low sensitivity to the drug.
The pharmacological agent will not be effective against:
- klebsiella;
- Pseudomonas aeruginosa;
- providence;
- Proteus mirabilis.
The exact mechanism of the drug's work remains unknown. Stopdiar has two types of action:
- bactericidal - destroys pathogenic microbes;
- bacteriostatic - retards the growth and development of microorganisms.
The mode of action depends on the dose taken: an average dose leads to a bacteriostatic effect, a high dose to a bactericidal one.
Bacteriostatic action Stopdiar is caused by a violation of the biosynthesis of necessary compounds in the microbial cell. As a result, it cannot reproduce.
Bactericidal effect Stopdiara is determined by the fact that high doses of it are capable of destroying the cell membrane. As a result of violation of the integrity of the cell membrane, microbes die.
In addition, the drug is able to inhibit the production of toxins by pathogenic microbes, which reduces irritation of intestinal epithelial cells and reduces the formation of fluid in the lumen of the digestive tract.
Stopdiar does not have a detrimental effect on non-pathogenic flora, therefore, when it is applied, dysbiosis does not develop.
In addition to its good effect on bacterial infections of the gastrointestinal tract, the drug also reduces the likelihood of their occurrence in viral diarrhea.
Release forms
Stopdiar is supplied in the form of tablets, capsules, suspensions.
Children are prescribed capsules or suspensions. The capsule contains 200 mg of the main component. In suspension, for every 5 ml of liquid there is 220 mg of nifuroxazide.
Symptoms for which Stopdiar is prescribed
Diarrhea
Stopdiar is prescribed for children:
- with acute and chronic diarrhea of bacterial etiology;
- with infectious chronic enteritis and colitis, accompanied by diarrhea;
- to prevent complications during gastrointestinal surgery.
Stopdiar can be prescribed for diarrhea of an unclear etiology, however, with signs of helminthic invasion, the drug is not used
Vomiting
The drug is prescribed for the purpose of stopping vomiting attacks accompanied by diarrhea. Stopdiar can be given to children with vomiting without loose stools.
Other symptoms
Stopdiar is included in the treatment of dysbiosis to reduce the number of harmful bacteria. This will allow the beneficial intestinal flora to develop normally.
Drug dosage depending on age
Stopdiar suspension for children
| Age | Single dose in ml | Number of appointments per day |
| 2-6 months | 2,5 — 5 | 2 |
| 6 months - 6 years | 5 | 3 |
| 6 - 18 years old | 5 | 3 |
Capsules
| Age | Single dose in mg | Number of appointments per day | Maximum daily dose in mg |
| 36 years | 200 mg | 3 | 600 |
| From 6 years old | 200 mg | 4 | 800 |
When Stopdiar can harm, or Contraindications to the appointment
The drug is prohibited for use when:
- intestinal obstruction or suspicion of it;
- allergies to drugs of a number of nitrofurans (nitrofurantoin, furazidine; furazolidone, nifuratel);
- hypersensitivity to the components of the drug.
The suspension is not offered to children under 2 months, and capsules - up to 3 years.
Adverse reactions from the use of Stopdiar
Usually, the child's body tolerates the medicine well, but negative reactions may appear.
Frequent
It:
- abdominal pain;
- nausea;
- increased diarrhea.
These symptoms do not require discontinuation of treatment.
Rare
Sometimes the child has a hypersensitivity to nitrofurans and drug components. In this case, an allergic reaction may occur in the form of a skin rash, respiratory failure. With such signs, the drug should be canceled in order to avoid life-threatening consequences.
Is an overdose possible
To date, there are no registered cases of Stopdiar overdose.
What drugs and how does Stopdiar interact
Due to the fact that nifuroxazide does not enter the bloodstream, its interaction with other drugs will not have a systemic effect on the body.
Stopdiar can interfere with the absorption of other medications used, so their combination should be avoided.
Experts do not recommend combining the use of Stopdiar capsules and drugs that have a depressing effect on the central nervous system.
Purchase of Stopdiar in a pharmacy
Is it possible without a prescription
The suspension is sold upon presentation of a prescription. The capsules are available without a prescription.
Are there analogues
The pharmacist can suggest, in addition to Stopdiar, other drugs with the same active substance. They may differ in price, amount of nifuroxazide and composition of additional components:
- Nifuroxazide Richter;
- Ekofuril;
- Enterofuril;
- Ersefuril;
- Lecor.
Average price for Stopdiar in Russia
The average price of the drug is 254 rubles.
How to store correctly
Store the drug out of the reach of children at temperatures below 25 ° C
The suspension must not be frozen and must be used within 2 weeks after the first opening of the bottle.
Reviews of doctors
Pediatricians give a positive response to this drug because of its spectrum and mechanism of action. Specialists often prescribe it to children with signs of infectious diarrhea.
Conclusion
To achieve a positive result, you must clearly follow the instructions for the drug and the recommendations of a specialist.
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