"Pangrol 10000" from the well-known company "Berlin-Chemie" is an enzyme agent that is in demand for some diseases of the digestive system. It is most often prescribed for adults with chronic pancreatitis, but it is sometimes prescribed for children.
In order for such a medicine to really help improve digestion, before using it, parents should learn more about the action of Pangrol, the indications for its use and the possible harmful effects on the child's body.
Dosage form and composition
Pangrol 10000 is presented in capsules, which are sold in plastic bottles of 20, 50 or 100 pieces. They have a cylindrical shape with rounded ends, size # 2, orange body and a greenish-yellow gelatin cap. Inside the capsule are cylindrical tiny beige tablets, the shell of which dissolves in the intestine.
The number in the name of the drug indicates the dosage of the main ingredient of "Pangrol" - pancreatin, and at the same time shows how many units of lipase are in one capsule. In addition to this enzyme, the drug also includes 9 thousand units of amylase, as well as protease in the amount of 500 units. Among the auxiliary compounds of the drug are castor oil, MCC, simethicone emulsion, dyes, croscarmellose sodium and other substances.
It should also be noted that "Pangrol" is produced in a higher dosage. In pharmacies, you can find capsules containing 25,000 units of lipase. They also have an orange-green shell, inside of which there are round mini-tablets, but the size of the capsule itself is larger (# 0). This product, called Pangrol 25000, is chosen for older children who need large doses of enzymes.
Operating principle
The pancreatin present in the capsules is obtained from the pancreas of pigs and contains enzymes that are needed for the normal digestion of carbohydrates, fats and protein compounds found in food. The use of "Pangrol" helps the pancreas if its function is impaired, and also helps to normalize digestion and, in general, has a positive effect on the digestive tract.
The capsule shell, made of gelatin, breaks down in the stomach, but the mini-tablet coating withstands the action of hydrochloric acid. This structure of the drug allows you to protect enzymes from inactivation by gastric juice. Since the tablets are small, they mix evenly with food and are distributed in the intestinal contents. As soon as they enter the small intestine, enzymes are released and pancreatin is included in the digestion process.
Indications
"Pangrol 10000" is used for various lesions of the pancreas, when the function of such an organ is impaired, for example, if the pancreas is inflamed, a tumor process is detected in it, it is partially or completely removed, or the organs of the digestive tract have been irradiated. The drug is also often prescribed to treat cystic fibrosis.
In addition, it can be used to eliminate temporary enzyme deficiencies caused by such problems:
- overeating;
- acute intestinal infection;
- eating fatty and fried foods;
- functional digestive disorder (non-infectious diarrhea);
- eating an excess of plant foods that are difficult to digest;
- irritable bowel syndrome.
Another reason for the use of "Pangrol" may be preparation for the examination of the abdominal cavity - capsules are prescribed for patients who are going to have an ultrasound or X-ray. Doctors can also include such an enzyme in the treatment of dysbiosis, lactase deficiency, atopic dermatitis and other problems. Capsules are also indicated for patients who are recovering from an infectious disease or surgery, so that food in their body is better absorbed.
At what age are children prescribed?
There is no age limit for the use of capsules, so the drug can even be prescribed to a newborn.
However, the use in infants and older children without prior consultation with a doctor is not recommended, since there are still some restrictions for the treatment of Pangrol.
Contraindications
Like other enzyme agents, Pangrol should not be taken in case of acute inflammation of the pancreas or in case of exacerbation of chronic pancreatitis. Capsules are also contraindicated in hypersensitivity to pancreatin or any inactive ingredient.
Side effects
Due to the intake of "Pangrol", the child may develop an allergic rash, bloating, loose stools, nausea, constipation or other unpleasant symptoms. In such a situation, it is necessary to inform the doctor about the side effect in order to adjust the treatment.
Instructions for use
The selection of the dose of "Pangrol 10000" for a particular child should be individual, since it is influenced by the disease itself and the patient's nutrition (the diet prescribed by the doctor). On average, one kilogram of baby's weight for each meal requires 500-1000 IU of lipase.
If the baby has cystic fibrosis, the dosage is also selected taking into account age, weight, feces analysis and diet composition. At the same time, it is not recommended to exceed the dose of 10 thousand lipase units per 1 kilogram of body weight per day.
Terms of sale and storage
"Pangrol 10000" refers to over-the-counter drugs, so there are no difficulties with buying it, but a specialist consultation to determine the required daily dose and treatment regimen is necessary. The average price of a jar with 20 capsules is 250-260 rubles.
The shelf life of the medication is 2 years and is indicated on the box. Until the date marked on the package, the product should be stored in a place where a small child cannot find the capsules. The optimum storage temperature is no higher than 25 degrees Celsius.
Reviews
More than 90% of the reviews left about Pangrol 10000 are positive. In them, such capsules are called effective and more affordable in comparison with analogues. According to mothers, the medicine is quite convenient to use, it has good tolerance and a quick healing effect.
In the majority of reviews, Pangrol has no drawbacks. Only occasionally there are complaints about the difficulty of using in infants, and some parents still call such a drug expensive.
Analogs
If it is not possible to give the child "Pangrol 10000", it can be replaced by another enzyme preparation containing pancreatin. Such analogs include such funds.
- "Mezim forte"... This medicine is produced by the Russian company Berlin-Pharma in the form of tablets. They have a shell, and each tablet is a source of 3500 U of lipase. In addition, there are tablets with a dosage of 10 thousand ("Mezim forte 10,000") and 20 thousand ("Mezim 20,000"), which are prescribed from the age of 3.
- "Creon"... An analogue of "Pangrol 10000" will be capsules "Creon 10000", but such a German medicine is also presented with a higher lipase content in one capsule - 25 and 40 thousand. Babies can be given "Creon Micro", since such granules are more convenient to dose for the smallest patients.
- "Panzinorm 10000"... Each capsule of this medicine from the "KRKA" company contains the same dosage of enzymes as in "Pangrol 10000", and such a drug costs a little less.
- "Pancreatin forte"... This is another affordable analogue from the Russian company Biosintez. The amount of lipase in one such tablet is at least 3850 IU, but this drug is not given to children under 3 years of age.
- Hermital... These capsules from the German manufacturer are presented in a dosage of 10,000, which makes it possible to replace Pangrol. In addition, they are produced in a dose of 25,000 and 36,000 lipase units.
- "Penzital"... One such coated tablet contains 6000 IU of lipase. The drug is manufactured in India and is quite cheap.
- Micrasim... Such capsules from the Russian company "AVVA RUS" are presented in the same dosages as "Pangrol". They contain pellets that dissolve in the small intestine.
All these and other funds are allowed in childhood, but should be used in babies only as directed by a specialist. It is not recommended to give enzymes to a child without consulting a doctor.
About whether enzymes are needed for dysbiosis, Dr. Komarovsky will tell in the next video.
