When choosing an antibiotic that helps eliminate an infectious disease, preference is given to agents that act on many types of bacteria. One of these drugs is "Flemoklav Solutab".
Release form and composition
The medication is presented as dispersible tablets, that is, it can dissolve when mixed with water, forming a suspension, which is why the word "solutab" is present in the name of the drug. The drug is produced in the Netherlands in four different dosages:
- 125 mg + 31.25 mg;
- 250 mg + 62.5 mg;
- 500 mg + 125 mg;
- 875 mg + 125 mg.
The first figure in the indicated dosage of the medication is the amount of amoxicillin, presented as a trihydrate. The second number is the amount of clavulanic acid contained in the preparation in the form of potassium clavulanate.
In addition to these main components, the medication contains crospovidone, saccharin, MCC, magnesium stearate, apricot flavor and vanillin. The auxiliary components of tablets with a dosage of 875 mg + 125 mg are slightly different - dispersed cellulose is added to them, and instead of apricot perfume, this medicine has lemon and tangerine flavors.
In appearance, all variants of "Flemoklav Solutab" are similar to each other, since they are oblong oval tablets of white or yellowish color, in the structure of which there are brown inclusions. There is no risk on the surface of the tablet, that is, its division into parts is not provided, however, there is a logo of the manufacturer and a three-digit figure that differs for tablets of different dosages (for example, on a drug with 125 mg of amoxicillin, you can see the number 421).
All types of medicine, except for the drug with the highest dosage, are packed in blisters of 4 pieces and sold in boxes of 20 tablets. As for "Flemoklav" with amoxicillin content at a dose of 875 mg, these tablets are sold 14 pieces in a pack and 7 pieces in one blister.
Operating principle
Amoxicillin, which is one of the main components of Flemoklav, belongs to penicillin antibiotics. It has a rather broad spectrum of bactericidal (destroying bacteria) effect on microbes that provoke infections of the respiratory tract, kidneys and other organs.
The presence of another active ingredient (clavulanic acid) in the tablets helps amoxicillin avoid destruction by beta-lactamases, enzymes produced by some strains of bacteria. Due to the combination with such an acid, the drug is effective against various types of staphylococci, enterococci, listeria, bacteroids, clostridia, escherichia, proteus, streptococci and other pathogens.
Indications
"Flemoklav Solutab" is used for various diseases, including:
- sinusitis;
- otitis;
- pharyngitis;
- angina;
- tracheitis;
- bacterial pneumonia;
- bronchitis;
- scarlet fever;
- skin infections;
- pyelonephritis;
- cystitis.
In addition, tablets with a dosage of 875 mg + 125 mg are prescribed for bacterial damage to the joints and bones, as well as for gynecological infections.
At what age is it assigned?
According to the annotation to the tablets, they can be given from 3 months of age. The use in children of the first months of life is also possible, but only with serious indications and under the supervision of a doctor. Babies who are already three months old are also given medicine only as prescribed by the doctor.
Tablets with the highest dose of amoxicillin are contraindicated up to 12 years of age, since the amount of antibiotic in such a drug (875 mg + 125 mg) is only suitable for patients weighing more than 40 kg.
Contraindications
The medication is not used in children with hypersensitivity to any of the components of the tablets, as well as with allergies to other penicillin or cephalosporin antibacterial drugs. It should also not be given to patients who have had liver damage or jaundice in the past with a combination of amoxicillin and clavulanic acid.
"Flemoklav" is not used for lymphocytic leukemia and infectious mononucleosis, as well as for influenza and other viral infections. The highest dosage tablets are contraindicated in severe renal impairment.
If the patient has any disease of the gastrointestinal tract, kidneys or liver, the question of taking Flemoklav should be decided by the attending physician individually.
Side effects
Taking "Flemoklav Solutab" can sometimes cause an allergic skin reaction or negative gastrointestinal symptoms, such as vomiting or abdominal pain. In some patients, pills have a negative effect on the liver or blood formation. In addition, the medication can cause the development of candidiasis or superinfection.
Instructions for use
In order to prevent the negative influence of "Flemoklav Solutab" on the stomach and intestines, taking the tablet is recommended immediately before meals. If the child can swallow it, then the drug is advised not to chew, but immediately drink water. However, the most common "childish" way of taking the medicine is to dissolve it in water (30-100 ml).
After thorough stirring, the resulting syrup is given to the patient in a dose appropriate for age and weight. If the child's age is from 3 months to 12 years, then for 1 kilogram of body weight of such a patient, 20-30 mg of amoxicillin is needed, and clavulanic acid is required from 5 to 7.5 mg. Often the drug is prescribed in the following dosages:
- a child weighing 5-12 kg (under two years old) - 125 mg + 31.25 mg twice a day;
- a patient weighing from 13 to 25 kg (at the age of 2-7 years) - 125 mg + 31.25 mg three times a day;
- a child who weighs 25-37 kg (usually this is the age of 7-12 years) - three times a day, 250 mg + 62.5 mg;
- for a patient weighing more than 40 kg - three times a day, 500 mg + 125 mg, or twice a day with a dosage of 875 mg + 125 mg.
If the infection is severe, the indicated dosages can be doubled, but the child should not receive more than 60 mg of amoxicillin per day for each kilogram of his weight, and for clavulanic acid, a dose of 15 mg / kg is considered the boundary.
The duration of the use of "Flemoklav" should be determined taking into account the severity of the disease, but usually the course of therapy does not exceed two weeks.
Overdose
If a child accidentally takes Flemoklav in a much higher dose than the doctor prescribed, it will lead to vomiting, diarrhea or severe nausea, which in severe poisoning threatens dehydration and electrolyte imbalance. In such a situation, you need to give the child activated charcoal and rehydration solution, and then see a doctor.
Interaction with other drugs
The absorption and effectiveness of Flemoklav is influenced by the intake of antacids, aminoglycosides, laxatives, ascorbic acid or glucosamine. When combined with bacteriostatic drugs, the effect of the tablets weakens, and when supplemented with an antibiotic with a bactericidal effect, on the contrary, the effect of the drug will be stronger.
Do not combine Flemoklav with anticoagulants, diuretics, digoxin, methotrexate and some other drugs that can be seen in the annotation to the tablets.
Terms of sale
"Flemoklav Solutab" refers to drugs that are sold by prescription, therefore, a doctor's examination is required before buying pills. The cost of the drug depends on the dosage of its active substances. For example, for a pack of tablets containing 125 mg of amoxicillin, you need to pay from 260 to 300 rubles, and a package of a medicine containing 250 mg of amoxicillin in each tablet costs about 400 rubles.
Storage conditions
The shelf life of dispersible tablets, with the exception of the drug with a dosage of 875 mg + 125 mg, is 3 years, but the drug with the highest dose of active substances is good for 2 years from the date of manufacture. It is recommended to store the medication at temperatures up to +25 degrees, choosing for this a dry place inaccessible to babies.
Reviews
Most of the reviews that parents and doctors leave about Flemoklav are positive. The advantages of the drug are called the possibility of use in infants, a convenient dosage form and a wide range of antibacterial effects. According to mothers, taking "Flemoklav Solutab" helped to quickly get rid of high fever, cough and other symptoms of infection.
Side effects during treatment with such a remedy are rarely noted.... The disadvantages of the medication mainly include the high price and large size of the tablets, somewhat inconvenient for children's use.
Analogs
If it becomes necessary to take instead of "Flemoklav Solutab" another drug with the same active compounds in the composition, the doctor prescribes:
- "Amoxiclav";
- "Augmentin";
- "Amoxiclav Kviktab";
- Ecoclave;
- "Panklav";
- "Arlet";
- "Klamosar";
- Panklav 2X;
- Augmentin EU;
- Augmentin SR ";
- "Medoklav";
- "Amoxivan" and others.
Such preparations are available in the form of a powder for preparing a suspension, dispersible tablets or coated tablets. Also, some of them are presented in an injectable form - a powder from which a solution for intravenous injections is made. All of them are used with the same indications as Flemoklav.
Instead of these drugs, the doctor may prescribe another penicillin or cephalosporin antibiotic, for example, "Zinnat", "Flemoxin Solutab" or "Suprax". If the patient is allergic to amoxicillin, antibiotics of other groups are prescribed, for example, "Sumamed", "Klacid", "Vilprafen" or "Macropen".
However, it is not recommended to give any antibacterial drugs to children without a doctor's examination.
Doctor Komarovsky will tell you when antibiotics are really needed in the next video.
